Clindamycin dosage modification may not be necessary in patients with renal disease. Includes Clindamycin (Systemic) indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. However, it was postulated from studies that when given every eight hours, accumulation should rarely occur. It cannot . Other uses for this medicine This medication has not been approved for any alternative uses other than those mentioned in the product information section. Always consult your health care provider or pharmacist to determine what medication and dosage are right for you. Clindamycin dosage modification may not be necessary in patients with renal disease. Indication: XACIATO (clindamycin phosphate) vaginal gel is a lincosamide antibacterial indicated for the treatment of bacterial vaginosis in female patients 12 years of age and older. You should never administer this medication to your dog unless prescribed by a veterinarian. Clindamycin hcl is sold under the brand names AntiRobe, ClindaRobe, Cleocin and Clinsol. Falagas and Gorbach ( 3 ), in a recent review, recommended clindamycin together with penicillin for severe skin and soft tissue infections due to group A streptococci or Clostridium . Topical applications: Clinical particulars. Current indications for the use of clindamycin: A critical review. Clindamycin is an antibiotic used for the treatment of bacterial infections. Topical: Apply the cream . Clindamycin hydrochloride capsules are also indicated in the treatment of serious infections due to susceptible strains of streptococci, pneumococci, and staphylococci. Give the dog some water after giving the pill to wash it down. Clindam (clindamycin) In Children. Clindamycin hydrochloride capsules, USP are indicated in the treatment of serious infections caused by susceptible anaerobic bacteria. INDICATIONS AND USAGE. It is efficacious against gram-positive aerobic bacteria (including most Staphylococcus and Streptococci spp), anaerobic bacteria, and some protozoal infections (including Toxoplasma).Clindamycin is approved by the FDA for use in dogs and cats with the following label indications: wounds, abscesses, and osteomyelitis . Clindamycin is a lincosamide antibiotic which is effective against many Gram-positive cocci and obligate anaerobes. Indication: Xaciato (clindamycin phosphate) vaginal gel is a lincosamide antibacterial indicated for the treatment of bacterial vaginosis in female patients 12 years of age and older. Clindamycin hydrochloride capsules, USP are also indicated in the treatment of serious infections due to susceptible strains of streptococci, pneumococci, and staphylococci. Clindamycin is used to treat certain types of bacterial infections, including infections of the lungs, skin, blood, female reproductive organs, and internal organs. Lincosamides such as clindamycin bind to the 50S subunit of the bacterial ribosome similarly to macrolides such as erythromycin and inhibit protein synthesis. It will not . Clindamycin, which is also known by a variety of other names including Antirobe, Antirobe, Cleocin, Aquadrops, Evoclin, and Dalacin, is one of the most commonly prescribed medications for dogs. If used as a topical foam, the typical recommendation is to apply as directed once per day. Adults: Serious infections - 150 to 300 mg every 6 hours. The recommended dosage is 1 000 mg loading dose followed by 500 mg every six hours for five to seven days. Intermittent hemodialysis Indication: XACIATO (clindamycin phosphate) vaginal gel is a lincosamide antibacterial indicated for the treatment of bacterial vaginosis in female patients 12 years of age and older. For more severe infections is 300 to 450 mg every 6 hours. The topical forms are used to treat acne. Clindamycin phosphate topical lotion is indicated in the treatment of acne vulgaris. In patients with moderate to severe liver disease, prolongation of clindamycin half-life has been found. In view of the potential for diarrhea, bloody diarrhea and pseudomembranous colitis, the physician should consider whether other agents are more appropriate (see CONTRAINDICATIONS, WARNINGS and ADVERSE REACTIONS). Therapeutic uses, prescribing information and product availability may vary . It is an antibiotic and helps to eliminate bacteria that are causing an infection. Dosage in Renal /Hepatic Impairment: Clindamycin dosage modification is not necessary in patients with renal or hepatic insufficiency. It works by slowing or stopping the growth of bacteria. Dosage and Administration: Administer one applicatorful (5 g of gel containing 100 mg of clindamycin) once intravaginally as a single dose at any time of the day. Administration instructions: clindamycin capsules should be taken with a full glass of water to avoid esophageal irritation. Its use should be reserved for penicillin . What is the dosage of Clindamycin? The FDA-approved dosage for cats using Antirobe oral drops is 11-33 milligrams per kilogram every 24 hours, given by mouth. Clindamycin is used to treat a wide variety of bacterial infections.It is an antibiotic that works by stopping the growth of bacteria.This antibiotic treats only bacterial infections. weight loss (unusual)—these side effects may also occur up to several weeks after you stop using this medicine. Clindamycin is a lincosamide antibiotic that has been approved by the US Food and Drug Administration for the treatment of anaerobic, streptococcal, and staphylococcal infections. Clindamycin injection is used to treat certain types of bacterial infections, including infections of the lungs, skin, blood, bones, joints, female reproductive organs, and internal organs. For oral dosage forms (capsules and solution): For treatment of bacterial infections: Adults—150 to 300 milligrams (mg) every 6 hours. INDICATIONS AND USAGE . Learn about its side effects, warnings, dosage, and more. Check with your doctor as soon as possible . If significant diarrhea occurs during therapy, this antibiotic should be discontinued (see BOXED WARNING). Disclaimer: This information is independently developed by CIMS based on clindamycin from various references and is provided for your reference only. It is useful for treating joint and bone infections (such as osteomyelitis), and infections in the abdomen.It is also used to treat tooth infections where other antibiotics have not worked. Clindamycin Phosphate Gel - Uses, Side Effects, and More Common Brand(S): Cleocin T, Clinda-Derm Generic Name(S): clindamycin phosphate View Free Coupon Children weighing 10 kilograms (kg) or more—Dose is based on body weight and must be determined by your doctor. The results indicated that the benzoyl peroxide/clin … Of note, dosing information is extrapolated from adult data and medication regimens for other indications; data using clindamycin and primaquine in children with PCP are not available. The dose for pediatric patients is 8 to 16 mg/kg/day divided in three or four equal doses. If you have questions, talk with the doctor. If you are 60 or older, use this medicine (clindamycin capsules) with care. Abdominal or stomach cramps, pain, and bloating (severe) diarrhea (watery and severe), which may also be bloody. M Smieja. Dosage and Administration: Administer one applicatorful (5 g of gel containing 100 mg of clindamycin) once intravaginally as a single dose at any time of the day. INDICATIONS AND USAGE. Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms 14,13 as well as topically for acne vulgaris. Together with rifampicin, uses for oral clindamycin include: Staphylococcal skin infections (cellulitis, impetigo, boils and . Indication: XACIATO (clindamycin phosphate) vaginal gel is a lincosamide antibacterial indicated for the treatment of bacterial vaginosis in female patients 12 years of age and older. However, it was postulated from studies that when given every eight hours, accumulation should rarely occur. These are available in liquid or capsule form, both to be taken orally 3-4 times a day. Indications and Usage. Several studies indicate that treatment with clindamycin may prevent recurrence and thereby eliminate the need … Description: Clindamycin, a lincosamide antibiotic, inhibits bacterial protein synthesis by reversibly binding to the 50S ribosomal subunit, thereby preventing the peptide bond formation, ribosome assembly and translation process. 4. Clindamycin is an antibiotic. Basic Information. Clindamycin hydrochloride capsules, USP are indicated in the treatment of serious infections caused by susceptible anaerobic bacteria. It is sold under brand names like Cleocin T, Clindagel, Cleocin HCl, Evoclin, Clindamycin Pediatric, Clindacin P, Cleocin Pediatric, Clindacin Pac, Clin Single Use, and Cleocin in 5 % dextrose. The solution, lotion, pledgets, and most brands of gel are applied twice a day. What is the dosage for oral clindamycin? CNS toxoplasmosis: clindamycin 600 mg IV q6h or clindamycin 450 mg-600 mg PO q6h + pyrimethamine 200 mg PO loading dose, then 50-7 5mg PO q24hd + leucovorin 10-20 mg q24h. Clindamycin is recommended for this indication in Anti-Infective Guidelines for Community-Acquired Infections as a first-line agent, together with penicillin (8,9). Clindamycin is commonly sold in capsule form. Staphylococcal bone and joint infections such as osteomyelitis, Peritonitis, Intra-abdominal sepsis, Meticillin-resistant Staphylococcus aureus (MRSA) in bronchiectasis, bone and joint infections, and skin and soft-tissue infections. The foam and one brand of the gel (Clindagel ®) are usually applied once a day. More severe infections - 300 to 450 mg every 6 hours. In patients with moderate to severe liver disease, prolongation of clindamycin half-life has been found. If you are breastfeeding while taking this medicine, call your doctor if your baby has diaper rash , redness or white patches in the mouth or throat, stomach discomfort, or diarrhea that is watery or bloody. for serious infections, 150-300 mg every 6 hours; for more severe infections, 300-450 mg every 6 hours; The dosages . Indications and Usage. Only 10% of clindamycin is eliminated renally. Clindamycin alone is a poor inducer of the methylase; as such, bacterial isolates can appear falsely susceptible to clindamycin when conventional antimicrobial … Cellulitis and skin abscess in adults: Treatment The content on this page is not medical advice and should be used for informational purposes only. Clindamycin has been reported to appear in breast milk in range of 0.5 to 3.8 mcg/mL; clindamycin has potential to cause adverse effects on breastfed infant's gastrointestinal flora; if oral or intravenous clindamycin is required by nursing mother, it is not a reason to discontinue breastfeeding, but alternate drug may be preferred; monitor . In overall improvement as rated by the physicians and patients, the combination gel was superior to clindamycin alone, and in 2 of the 3 studies, to benzoyl . Indications and Usage for Clindamycin Capsules. The dose is usually 8 to 16 milligrams . It was observed that 10% of the Streptococcus viridans bacteria were resistant to clindamycin. Clindamycin hydrochloride capsules are indicated in the treatment of serious infections caused by susceptible anaerobic bacteria. Dosage and Administration: Administer one applicatorful (5 g of gel containing 100 mg of clindamycin) once intravaginally as a single dose at any time of the day. Clindamycin is a medicine used to treat different types of bacterial infections. Clindamycin oral capsule is available as a generic drug and as the brand-name drug Cleocin. Clindamycin (Cleocin) is used to treat serious infections caused by bacteria. Caution: Birds receiving this drug are at an increased risk of secondary yeast infections (sour crop). Topical clindamycin comes as a foam, a gel, a solution (liquid), a lotion, and a pledget (swab) to apply to the skin. Dosage and Administration: Administer one applicatorful (5 g of gel containing 100 mg of clindamycin) once intravaginally as a single dose at any time of the day. Can J Infect Dis 1998;9 (1):22 . Clindamycin is indicated in the treatment of serious infections caused by susceptible anaerobic bacteria. The dose is less than this if it is prescribed for a child. It is most often used to treat birds with wounds, bumblefoot, and osteomyelitis (bone infections). It is used to treat a wide variety of bacterial infections in the lungs, skin, blood and internal organs. Oral- The recommended dose range is 150 to 300mg two times per day. December 07, 2021 16: 15 ET |Useful resource: Daré Bioscience, Inc. Prescribing particulars sustains putting of XACIATO as an preliminary line selection for the remedy of microbial vaginosis This notes the preliminary FDA-approved merchandise in Daré's profile of potential preliminary in classification development prospects Strategic partnering conversations steady; Convention phone name . Dosage and Administration. IV- The recommended dose range is 200 to 600 mg three times per day. Clindamycin is a semisynthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent compound lincomycin. For pediatric patients the recommended dose is 8 to 20 mg/kg/day divided into 3 or 4 equal doses. Clindamycin remains the second drug of choice next to penicillin in treating odontogenic infections. Most of the time, this reaction has signs like fever, rash, or swollen glands with problems in body organs like the liver, kidney, blood, heart, muscles and joints, or lungs. Clindamycin is in a class of medications called lincomycin antibiotics. Indications and dose For CLINDAMYCIN. Clindamycin is a semisynthetic antibiotic produced by a 7 (S)-chloro . Apply topical clindamycin at around the same time (s) every day. By continuing to browse this site you are agreeing to our use of cookies. Sometimes, clindamycin is combined with other faster-acting malaria-fighting drugs However, this approach is not mentioned on clindamycin's list of FDA-approved indications [6, 7, 2]. Indication: XACIATO (clindamycin phosphate) vaginal gel is a lincosamide antibacterial indicated for the treatment of bacterial vaginosis in female patients 12 years of age and older. Clindamycin For Cats Dosage Whatever the case, it is extremely important to follow your veterinarian's instructions completely and to always finish out the full course of an antibiotic. 12 It has a relatively narrow spectrum of activity that includes anaerobic bacteria as well as gram . It works by slowing or stopping the growth of bacteria. It is available in different dosage forms such as a tablet, capsule, injection, gel, cream, and lotion. In patients with moderate to severe liver disease, prolongation of clindamycin half-life has been found. Antibiotics such as clindamycin will not work for . However, it was postulated from studies that when given every eight hours, accumulation should rarely occur. Clindamycin helps prevent bacterial growth on the skin that can lead to clogged pores, whiteheads, blackheads, pimples, and other blemishes. Clindamycin is indicated for the treatment of: Serious infections caused by anaerobic bacteria, including intra-abdominal infections, skin and soft tissue infections. The dosages for clindamycin capsules for adults are:. For more severe infections, 300 to 450 mg every 6 hours. Clindamycin dosage modification may not be necessary in patients with renal disease. You may also receive a topical gel that can be used to treat skin or vaginal infections or acne. Clindamycin is an antibiotic which is given to treat serious bacterial infections. increased thirst. Clindamycin hydrochloride capsules, USP are also indicated in the treatment of serious infections due to susceptible strains of streptococci, pneumococci, and . Therefore, dosage modification in patients with . Its major disadvantage is its propensity to cause antibiotic-associated diarrhea, including Clostridioides difficile colitis. In oral and parenteral . Each mL contains the equivalent of 150 mg clindamycin, 0.5 mg disodium edetate and 9.45 mg benzyl alcohol added as preservative in each mL. Clindamycin Injection, USP in vials contains clindamycin phosphate, a water soluble ester of clindamycin and phosphoric acid. Dosage for Clindam (clindamycin) The dose of Clindamycin for adults is 150 to 300 mg every 6 hours. Pharmacokinetics: Absorption: As clindamycin hydrochloride: Rapidly absorbed from the gastrointestinal tract (approx 90%). {{configCtrl2.info.metaDescription}} This site uses cookies. In patients with moderate to severe liver disease, prolongation of clindamycin half-life has been found. CLEOCIN HCl Capsules contain clindamycin hydrochloride equivalent to 75 mg, 150 mg, or 300 mg of clindamycin.
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